Vitamin B-12 (Cobalamin) is a vital water-soluble vitamin essential for the proper functioning of the nervous system, red blood cell production, and DNA synthesis. This test measures the concentration of Vitamin B-12 in the blood to evaluate deficiency, absorption issues, or related metabolic disorders.

A deficiency of Vitamin B-12 can lead to megaloblastic anemia, nerve damage, memory problems, fatigue, and tingling or numbness in hands and feet. It is especially common in individuals with vegetarian/vegan diets, older adults, and patients with intestinal disorders like gastritis, celiac disease, or pernicious anemia.